CIRCULATING TUMOUR DNA DYNAMICS PREDICT RECURRENCE IN STAGE III MELANOMA PATIENTS RECEIVING NEOADJUVANT IMMUNOTHERAPY

Circulating tumour DNA dynamics predict recurrence in stage III melanoma patients receiving neoadjuvant immunotherapy

Abstract Background Neoadjuvant therapy improves recurrence-free survival (RFS) in resectable stage III cutaneous melanoma.However, accurately predicting individual recurrence risk remains a significant challenge.We investigated circulating tumour DNA maison alhambra libbra (ctDNA) as a biomarker for recurrence in measurable stage IIIB/C melanoma p

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Regulatory mechanisms of the green alga Ulva lactuca oligosaccharide via the metabolomics and gut microbiome in diabetic mice

Type 2 diabetes (T2D) has emerged as one of the most acute public health diseases of the present time, which increases with the population ageing.This study aimed firestorm darts to evaluate the hypoglycaemic activity of Ulva lactuca oligosaccharide (ULO) under ageing-related diabetes conditions in an animal model.The results demonstrated that ULO

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Integration of a peer practitioner in a hospital unit for patients with psychotic disorders: an exploratory qualitative study

IntroductionStudies on the integration of peer mental health practitioners (PMHP) in hospitals are sparse, despite significant benefits being reported for patients and professionals.The integration of PMHP requires the consideration of several wx gloves parameters and a change in the culture of care.This study aims to understand the impact of the i

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